From what I've heard you can burn up an engine really quickly by adding a supercharger to it, plus I believe supercharges work better with engines that have valves (intake/exhaust)
Cause you need something to stop the fuel/air mixture, so the combustion chamber can be charged full of said fuel air mixture..... I have heard of some 2stroke bikes that have supercharges, but I hear they can take a While to get up to a speed where the charging system is actually being a benefit, um if you add more air for combustion your also adding heat, and if the idea is to stay under 240F it might be a bad idea, unless you've got an R/C gambit up your sleeve like liquid cooled R/C engine